Journal of Veterinary and Biomedical Sciences
(ISSN: 2659 – 0743)
Volume 5, No. 1, 2023
Pages 1-9
DOI: 10.36108/jvbs/3202.50.0110
Evaluation of Antibody Titre in Dogs Vaccinated against Canine Parvovirus in Jos, Plateau State, Nigeria
1*Ogbu, K.I., 1Abdullahi M.A., 1Momoh-Abdullateef, H., 2Chukwudi, I.C., 3Bata, I.S., 4Ezema, K.U., 5Salami, A.C., 6Sabo, J.A., 1Aiyedun, P.O., 7Emennaa, C.I., 7Ihenatuoha, A.U., 8Tion, M.T., 9Malgwi R.I., 9Okonkwo, R.A
1Department of Animal Health, Federal College of Animal Health and Production Technology, National
Veterinary Research Institute, Vom, Plateau State, Nigeria
2Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Nigeria,
Nsukka, Enugu State, Nigeria
3Department of Veterinary Laboratory Technology, Federal College of Animal Health and Production Technology,
National Veterinary Research Institute, Vom, Plateau State, Nigeria
4Veterinary Teaching Hospital, University of Maiduguri, Borno State, Nigeria
5Department of Agricultural Technology, Federal Polytechnic Nasarawa, Nasarawa State, Nigeria
6Department of Public Health, Federal College of Animal Health and Production Technology,
National Veterinary Research Institute, Vom, Plateau State, Nigeria
7Department of Environmental Health, Federal College of Animal Health and Production Technology,
National Veterinary Research Institute, Vom, Plateau State, Nigeria
8Department of Veterinary Medicine, College of Veterinary Medicine, Federal University of Agriculture, Makurdi, Benue State, Nigeria
ABSTRACT
Canine parvoviral enteritis is a highly contagious disease with fatal outcomes, in most cases populations with high morbidity and mortality rate. The study was conducted to determine the immune status of dogs vaccinated against Canine Parvovirus (CPV) using enzyme linked immunosorbent assay (ELISA). Sixty randomly selected dogs were used for the study, out of which four had no level of determined antibody titre (1-2 S – unit), fifty six had protective immunity (3-6 S-unit) which comprised 24 (40%) males and 36(60%) females. Among the males, 23(95.83%) were protective while 33(91.67%) among the females were protective. A total of 17 dogs were puppies and all had protective immunity (3-6 S-unit) while 43 were adults out of which 39 (90.70%) had protective immunity (3-6 S-unit). A total of 30 dogs were sampled from each local government area out of which 28(93.33%) had protective immunity (3-6 S unit) in each local government. The breeds included in the study were Caucasian, Mongrel, Rottweiler, Lhasa, Bull mastiff and German Shepard out of which all had protective immunity 56(93.33%) (3-6 S-unit) except 4(6.67%) for Caucasian that were unprotected. Based on the number of primary vaccinations, 3 dogs had single, 4 dogs had double and 52 dogs had triple primary vaccination out of which 56 dogs had protective antibody titre (3-6 S-unit). There was no significant difference (P>0.05) between sex, age, location, breeds and level of immunity while there was a significant difference (P< 0.05) between the number of primary vaccination and immune titre of the dogs sampled
Keywords: Canine Parvovirus, Antibody titre, Dog, Evaluation, Jos